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Endovascular treatment of giant hepatic hemangiomas: a systematic review and meta-analysis

Sofia Malosso Tronconi1, João Felipe Federici de Almeida1, Ana Terezinha Guillaumon1

  • 1Universidade Estadual de Campinas - Unicamp, Faculdade de Ciências Médicas - FCM, Hospital de Clínicas, Campinas, SP, Brasil.

Jornal Vascular Brasileiro
|December 17, 2025
PubMed

Giant hepatic hemangiomas are benign vascular lesions that may cause abdominal pain, compression of adjacent structures, bleeding, and thrombotic complications. Management of symptomatic cases is challenging, especially for larger lesions. This systematic review and meta-analysis evaluated the efficacy and safety of endovascular treatment through transarterial embolization, focusing on the embolization agents employed, reductions in tumor diameter, and associated complications. The results showed significant reductions in mean hemangioma diameter, with low rates of severe complications. This treatment emerges as a promising minimally invasive option for symptomatic or unresectable cases.

Keywords:
endovascular treatmenthepatic hemangiomameta-analysissystematic reviewtherapeutic embolization

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