The cost of a checkbox
1From the Department of Emergency Medicine, Prisma Health-Upstate, University of South Carolina School of Medicine, Greenville, SC.
The Journal of Trauma and Acute Care Surgery
|December 17, 2025
Summary
Routine urine drug screens in trauma care are outdated and rarely inform treatment decisions. These tests can lead to misinterpretations in legal settings and should be replaced with interview-based methods.
Area of Science:
- Trauma Care
- Clinical Diagnostics
- Forensic Toxicology
Background:
- Urine drug screens (UDS) are frequently included in trauma care protocols.
- Current UDS panels are based on outdated workplace testing standards.
- These tests often fail to provide actionable information for acute trauma management.
Purpose of the Study:
- To evaluate the utility and impact of routine urine drug screening in trauma care.
- To identify the limitations and potential harms associated with UDS in trauma patients.
- To recommend alternative screening strategies aligned with current clinical guidelines.
Main Methods:
- Review of existing trauma care protocols and UDS utility.
- Analysis of the clinical and legal implications of UDS results.
- Comparison of UDS with interview-based screening methods.
Main Results:
- UDS rarely informs immediate trauma care decisions or establishes acute intoxication.
- UDS can lead to diagnostic anchoring and false assurance of drug abstinence.
- UDS results may be misinterpreted in legal contexts, attributing fault without evidence of impairment.
Conclusions:
- Routine urine drug screening should be removed from trauma care order sets.
- Validated, interview-based screening methods should be prioritized.
- Confirmation testing is recommended when UDS is clinically indicated.
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