Related Experiment Video
Updated: Jan 8, 2026

Non-invasive Assessment of Microvascular and Endothelial Function
Published on: January 29, 2013
Classification of capillary damage in patients with type 2 diabetes mellitus: Clinical parameters obtained through
Luis Fernando Flota-Cervera1, Francisco José González-García2, Abdel Kerim Raffoul-Orozco2,3
1CEDIME Instituto Vascular, Mérida, Mexico.
Abstract:
ObjectiveDiabetes mellitus (DM) significantly affects microcirculation, leading to microvascular abnormalities that can result in severe systemic complications. Capillaroscopy is a non-invasive and painless method for observing capillary microvasculature, allowing for the assessment of microcirculatory damage. While it is known primarily for its application in rheumatic diseases, recent studies have emphasized its importance in non-rheumatic conditions, such as DM. This growing relevance has led to the aim of developing a classification system for capillary damage in diabetic patients.MethodsCross-sectional study. Eighty randomly selected patients with type 2 diabetes mellitus (T2DM) were evaluated using capillaroscopy to assess capillary damage and establish a classification system.ResultsCapillary damage was observed in all participants (100%), with greater severity associated with longer diabetes duration. Patients were categorized based on the severity of their damage.ConclusionsThe classification system identified three degrees of capillary damage: an early grade, which can be subdivided into initial or established; an intermediate grade, which can also be initial or established (both treatable for potential reversibility); and an advanced grade, which appears to be irreversible. This classification aids in better understanding and managing microvascular damage in diabetic patients.
More Related Videos
05:17A Reproducible Computerized Method for Quantitation of Capillary Density using Nailfold Capillaroscopy
Published on: October 27, 2015
07:18Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
Published on: February 18, 2022
Related Concept Videos
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Diabetes: Symptoms, Diagnosis, and Complications
Pathophysiology of Diabetes
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Assessment of the Cardiovascular System III: Palpation
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above...
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
Diabetes Mellitus: Type 2 and Gestational