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Antihypertensive Drugs: Angiotensin-Converting Enzyme Inhibitors

Antihypertensive Drugs: Angiotensin-Converting Enzyme Inhibitors

Angiotensin-converting enzyme (ACE), a vital component of the renin-angiotensin-aldosterone system, is abundant in lung endothelial cells. ACE converts the inactive decapeptide, angiotensin I, into the active octapeptide, angiotensin II. This potent vasoconstrictor narrows blood vessels, increasing resistance to blood flow and elevating blood pressure. Angiotensin II also stimulates aldosterone production, encouraging kidney cells to reabsorb more sodium and water from urine, thereby increasing...

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Updated: Jan 8, 2026

Assessing Murine Resistance Artery Function Using Pressure Myography

Assessing Murine Resistance Artery Function Using Pressure Myography

Published on: June 7, 2013

Kininogen Deficiency Elevates Blood Pressure in Mice

Yusuke Ohnaka^1,2, Ryusho Kariya^1,2, Satoshi Tsukamoto^1,2

¹Laboratory of Molecular Cellular Biology, School of Pharmaceutical Sciences, Kobe Gakuin University, Japan.

Hypertension (Dallas, Tex. : 1979)

|December 17, 2025

Summary

No abstract available in PubMed .

Keywords:

blood pressure inflammation kininogen mice, knockout vasodilator agents

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