Spinal Cord Stimulation in Schwannomatosis: A Case Report
Caleb Graham1, Ivan Chew, Justin Jackson
1From the UT Southwestern Medical Center, Dallas, Texas .
A&A Practice
|December 17, 2025
Summary
Spinal cord stimulation (SCS) effectively managed chronic lower extremity pain in a patient with schwannomatosis refractory to standard treatments. This case highlights SCS as a potential advanced therapy for complex neuropathic pain conditions.
Area of Science:
- Neurology
- Pain Medicine
- Neurosurgery
Background:
- Schwannomatosis can cause debilitating chronic pain.
- Refractory neuropathic pain poses significant treatment challenges.
Purpose of the Study:
- To evaluate the efficacy of spinal cord stimulation (SCS) for chronic lower extremity pain in a patient with schwannomatosis.
- To explore expanded indications for advanced interventional pain procedures.
Main Methods:
- A 48-year-old female patient with schwannomatosis and refractory lower extremity pain underwent a percutaneous trial of SCS.
- Following a successful trial, permanent SCS implantation was performed.
Main Results:
- The patient achieved near-complete and sustained elimination of neuropathic pain post-permanent SCS implantation.
- The treatment was effective despite failure of previous surgical, interventional, and medical therapies.
Conclusions:
- Spinal cord stimulation can be a viable and effective treatment option for refractory neuropathic pain associated with schwannomatosis.
- Advanced interventional pain procedures like SCS may offer solutions for complex pain conditions beyond current indications.
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