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Related Experiment Videos

Lupus pericarditis.

N Wolkove, H Frank

    Canadian Medical Association Journal
    |December 21, 1974
    PubMed
    Summary
    This summary is machine-generated.

    Systemic lupus erythematosus (SLE) can present as pericarditis, often misdiagnosed. Diagnosing SLE involves finding LE cells in pericardial fluid via pericardiocentesis, even with negative serology.

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    Area of Science:

    • Rheumatology
    • Cardiology
    • Internal Medicine

    Background:

    • Pericarditis is a common manifestation of systemic lupus erythematosus (SLE).
    • SLE-related pericarditis is frequently misdiagnosed as viral pericarditis when it is the initial presenting symptom.
    • Screening for collagen diseases is crucial in patients with unexplained pericarditis, particularly women.

    Purpose of the Study:

    • To highlight a case of SLE presenting primarily with pericarditis.
    • To emphasize the diagnostic utility of LE cells in pericardial fluid.
    • To review the literature on pericarditis in SLE.

    Main Methods:

    • Case report of a patient diagnosed with SLE after pericardiocentesis.
    • Demonstration of LE cells in pericardial fluid using Wright's stain.

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  • Literature review on the incidence and diagnosis of pericarditis in SLE.

    • Main Results:

    • Diagnosis of SLE was confirmed by identifying LE cells in pericardial fluid.
    • Literature suggests pericarditis is more common in SLE than previously thought.
    • Misdiagnosis of SLE pericarditis as viral pericarditis is a significant issue.

    Conclusions:

    • Pericarditis can be the primary presentation of SLE.
    • Diagnostic pericardiocentesis with LE cell analysis is valuable for SLE diagnosis, especially with negative serology or atypical presentations.
    • Consider SLE in the differential diagnosis of pericarditis, particularly in women.