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Published on: December 1, 2023
A Scoping Review to Map Health Outcomes in Inducible Laryngeal Obstruction
S F Ludlow1,2, L J Holmes3,4, L Simpson5
1Manchester Airways Service, Manchester University NHS Foundation Trust, Manchester, UK.
This review found varied outcome measures for inducible laryngeal obstruction (ILO), with few assessing personal and environmental impacts. Standardized measures are needed to capture the full scope of ILO
Area of Science:
- Laryngology and Respiratory Medicine
- Rehabilitation and Allied Health
- Health Services Research
Background:
- Inducible laryngeal obstruction (ILO) is a breathing disorder characterized by inappropriate laryngeal closure.
- Outcome measures are crucial for monitoring health status changes in ILO patients.
- A comprehensive review of existing measures is needed to guide treatment and identify gaps in current tools.
Purpose of the Study:
- To systematically evaluate outcome measures reported in the literature for individuals with ILO.
- To identify consistency in measurement for evidence synthesis in ILO treatment and management.
- To assess if current measures align with the World Health Organization International Classification of Functioning, Disability and Health (WHO-ICF) framework.
Main Methods:
- A systematic literature search was conducted across multiple databases (MEDLINE, EMBASE, CINAHL, Scopus, PsycINFO, Web of Science, Google Scholar) from December 2023 to December 2024.
- Two independent reviewers screened titles, abstracts, and full texts, extracting data using Covidence software.
- Outcomes were categorized by measurement type and alignment with WHO-ICF components.
Main Results:
- A total of 49 full-text articles were included after screening 658 titles and abstracts.
- Patient-reported outcomes were most common (97%), followed by clinician-reported (31%) and performance outcomes (26%).
- While body function, structure, and activity limitations were often considered, personal and environmental factors were rarely addressed within the WHO-ICF framework.
Conclusions:
- Significant variation exists in the outcome measures used in current ILO research.
- Measures assessing personal and environmental impacts of ILO are notably infrequent.
- There is a critical need to establish a consensus core outcome set for ILO research and clinical practice to ensure comprehensive impact assessment and facilitate evidence synthesis.
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