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Excimer-to-monomer switching in a pyrene HOF for discriminative neurotransmitter sensing
Wei Zhang1, Ziyao Zhang1, Gongxun Bai1
1Key Laboratory of Rare Earth Optoelectronic Materials and Devices of Zhejiang Province, Institute of Optoelectronic Materials and Devices, College of Optical and Electronic Technology, China Jiliang University, Hangzhou 310018, People's Republic of China. huixu@cjlu.edu.cn.
Abstract:
A pyrene-based HOF (PFC-1) enables excimer-to-monomer switching that affords the first ratiometric fluorescence discrimination of four similar monoamine neurotransmitters (5-HT, NE, Adr, DA). PFC-1 shows rapid response and high sensitivity, including a 36 nM LOD for 5-HT, and can be integrated into a smartphone platform for portable, point-of-care detection.

