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Applying the Knowledge-to-Action Framework to Implement and Evaluate an Evidence-Based Functional Exercise Program
Zhuzhu Qin1,2, Xinxin Ye3, Huanju Liu4
1Department of Orthopedics, People's Hospital of Deyang City, Deyang, Sichuan, People's Republic of China.
Clinical Interventions in Aging
|December 18, 2025
Summary
This study developed an evidence-based rehabilitation program for elderly patients after total knee arthroplasty (TKA). The program significantly improved pain control and knee function post-surgery.
Area of Science:
- Orthopedic Surgery
- Rehabilitation Medicine
- Geriatric Care
Background:
- Total knee arthroplasty (TKA) is a common procedure for elderly patients with knee osteoarthritis.
- Postoperative rehabilitation is crucial for optimal functional recovery and patient satisfaction.
- Current rehabilitation protocols may not be fully optimized for the unique needs of elderly TKA patients.
Purpose of the Study:
- To develop a systematic, evidence-based rehabilitation intervention for elderly TKA patients.
- To incorporate stakeholder input into the intervention design.
- To evaluate the impact of the developed intervention on patient outcomes.
Main Methods:
- A Knowledge-to-Action (KTA) Framework guided the study.
- Systematic literature synthesis identified 17 evidence-based recommendations.
- Expert panels and stakeholder interviews informed intervention development.
- A quasi-experimental study assessed preliminary efficacy in 60 patients.
Main Results:
- The intervention group showed significantly improved postoperative pain control (P < 0.05).
- Enhanced range of motion and knee function were observed in the intervention group (P < 0.05).
- No baseline differences existed between the intervention and control groups.
Conclusions:
- The evidence-based rehabilitation program significantly improved functional recovery and pain management compared to standard care.
- This structured intervention framework leads to clinically meaningful improvements in early postoperative outcomes after TKA.

