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Updated: Jan 8, 2026

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Transcatheter mitral valve replacement in a complex mitral annular calcification anatomy.
Fabrizio Tomai1, Giovanni De Persio1, Roberto Celotto1
1Department of Cardiovascular Sciences, European Hospital and Aurelia Hospital, Via Portuense 700, 00148 Rome, Italy.
Transcatheter mitral valve replacement (TMVR) presents challenges in patients with severe mitral annular calcification (MAC) and prior aortic valve replacement. This case highlights managing complications like circulatory arrest and cardiac tamponade during complex percutaneous interventions.
Area of Science:
- Cardiology
- Interventional Cardiology
- Medical Devices
Background:
- Transcatheter mitral valve replacement (TMVR) offers an alternative to surgery for high-risk patients, especially those with severe mitral annular calcification (MAC).
- Pre-existing self-expanding transcatheter aortic valve prostheses complicate TMVR procedures, increasing risks like left ventricular outflow tract obstruction.
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