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Consideration of Cardiovascular Morbidities in the Relationship between Ambient Air Pollution Exposure and
Sneha Kannoth1,2, Kavitha Ganesan2, Brandi Vollmer2,3
1Department of Environmental Medicine, Icahn School of Medicine at Mount Sinai, 17 E. 102nd Street CAM Building, 3 West One Gustave L. Levy Place, New York, NY 10029, USA.
Purpose Of Review:
Studies suggest ambient air pollution increases risk of individual-level adverse COVID-19 outcomes. Our review seeks to understand how air pollution influences adverse COVID-19 outcomes, by identifying how researchers accounted for cardiovascular morbidity, a predominant COVID-19 risk factor that is strongly linked to air pollution exposure.
Recent Findings:
Our review primarily consisted of retrospective cohorts from the US and Europe, that examined both historical and short-term air pollution. Studies typically found that air pollution was associated with greater risk of individual-level adverse COVID-19 outcomes and adjusted for cardiovascular morbidities as confounders. Few hypothesized cardiovascular morbidity as a mediator or effect modifier in this relationship.
Summary:
Improved understanding of cardiovascular morbidity's potential role as an effect modifier or mediator can help better explain the link between air pollution and COVID-19, in addition to identifying and assisting populations that may be at greater risk for adverse pandemic outcomes.
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