Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Postmyocardial infarction ventricular septal defect outcomes: Partial versus full presurgical hemodynamic support.

JTCVS open·2026
Same author

Ustiloxins and Ustilaginoidins in the Sclerotia Generated from Rice False Smut Balls and Their Contents.

Toxins·2026
Same author

Impact of aortic root surgery during transcatheter aortic valve explant.

JTCVS structural and endovascular·2026
Same author

Iliac artery involvement determines optimal therapy in acute uncomplicated type B aortic dissection.

JTCVS structural and endovascular·2026
Same author

Endovascular arch repair using a novel single branch arch stent graft: 30-Day results from the chronic dissection arm of the NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness investigational device exemption study.

JTCVS structural and endovascular·2026
Same author

Standardized End Point Definitions for Clinical Trials in Thoracic Aortic Repair: A Consensus Report From the ARCH-Academic Research Consortium.

Circulation·2026

Related Experiment Video

Updated: Jan 8, 2026

Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation
09:32

Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation

Published on: September 19, 2018

15.8K

Growth Prediction of Type B Aortic Dissections Using Wall-Stress-Driven Finite Element Simulation Based on the

Xue Liang, Marc-Philipp H Schmid, Minliang Liu

    Medrxiv : the Preprint Server for Health Sciences
    |December 18, 2025
    PubMed
    Summary

    A new computational framework accurately predicts aortic growth in patients with Type B aortic dissection (TBAD). This tool aids in managing uncomplicated TBAD by forecasting disease progression for timely intervention.

    More Related Videos

    Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery
    06:18

    Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery

    Published on: December 6, 2024

    969
    Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
    13:07

    Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

    Published on: January 15, 2022

    4.3K

    Related Experiment Videos

    Last Updated: Jan 8, 2026

    Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation
    09:32

    Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation

    Published on: September 19, 2018

    15.8K
    Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery
    06:18

    Intravascular Ultrasound Image-Based Finite Element Modeling Approach for Quantifying In Vivo Mechanical Properties of Human Coronary Artery

    Published on: December 6, 2024

    969
    Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression
    13:07

    Optical Coherence Tomography Based Biomechanical Fluid-Structure Interaction Analysis of Coronary Atherosclerosis Progression

    Published on: January 15, 2022

    4.3K

    Area of Science:

    • Biomedical Engineering
    • Computational Mechanics
    • Cardiovascular Research

    Background:

    • Type B aortic dissection (TBAD) involves a tear in the descending aorta, leading to potential complications.
    • Uncomplicated TBAD management relies on optimal medical therapy (OMT), necessitating accurate prediction of disease progression.
    • Predicting aortic growth is crucial for determining the optimal timing for intervention in TBAD patients.

    Purpose of the Study:

    • To extend a finite element (FE)-based tissue growth framework for predicting the precise geometry and diameter growth of TBAD.
    • To develop and validate a computational model for patient-specific TBAD growth forecasting.

    Main Methods:

    • Utilized the unified-fiber-distribution (UFD) model for aortic wall mechanics and a novel centerline-based algorithm for material coordinate determination.
    • Employed a linear kinematic growth law linked to local wall stress.
    • Performed inverse FE analysis on patient-specific geometries from serial CT scans to derive growth parameters, then simulated forward growth.

    Main Results:

    • The computational framework accurately predicted patient-specific aortic geometries and dimensions, closely matching in vivo measurements.
    • Maximum diameter error was below 3.5%, and mean diameter error was below 4% across all patients.
    • Demonstrated high fidelity in forecasting TBAD progression.

    Conclusions:

    • The developed computational framework shows significant potential for supporting clinical decision-making in managing uncomplicated TBAD.
    • Accurate, patient-specific growth forecasts can guide therapeutic strategies and intervention timing.
    • This FE-based approach offers a promising tool for personalized TBAD management.