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Artificial intelligence based real-time segmentation and feature tracking in urological retroperitoneal robotic
Luca A Morgantini1, Rebecca Canneto2, Rogerio G Nespolo3,4
1Department of Urology, University of Illinois at Chicago, Chicago, IL, USA - Lmorga5@uic.edu.
Minerva Urology and Nephrology
|December 18, 2025
Summary
This study developed an AI framework for real-time guidance in robotic retroperitoneal surgery. The AI enhances spatial orientation and training for surgeons performing complex procedures like nephrectomies.
Area of Science:
- Robotics and Artificial Intelligence in Surgery
- Medical Imaging and Computer Vision
- Surgical Navigation Systems
Background:
- Robotic-assisted surgery, especially with the da Vinci Single-Port (SP) system, offers precision in confined spaces like the retroperitoneum.
- Retroperitoneal anatomy presents significant spatial orientation challenges for surgeons, particularly those new to the field.
- This research addresses the need for improved visualization and guidance in SP retroperitoneal procedures.
Purpose of the Study:
- To develop and validate an Artificial Intelligence (AI)-based framework.
- To enable real-time segmentation and feature tracking during SP retroperitoneal robotic-assisted nephrectomies.
- To enhance spatial awareness and surgical precision in challenging anatomical locations.
Main Methods:
- Utilized a convolutional neural network (CNN) based on YOLACT++ for instance segmentation.
- Trained the AI model on annotated video frames from 15 patients undergoing SP nephrectomies.
- Performed real-time segmentation and detection of key anatomical landmarks and surgical instruments.
Main Results:
- Achieved high Area Under the Precision-Recall Curve (AUPRC) values: 0.759-0.901 for landmarks and up to 0.887 for instruments.
- Demonstrated AI's capability for real-time analysis of surgical video feeds.
- Identified limitations including a small dataset and variable segmentation precision for certain structures like the ureter.
Conclusions:
- The AI framework shows significant potential for real-time surgical guidance in SP retroperitoneal procedures.
- This technology can potentially improve novice surgeon training and streamline complex retroperitoneal surgeries.
- Future work includes dataset expansion, accuracy improvement, and integration into live surgical environments.

