Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

890
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
890
Pulmonary Tuberculosis II01:28

Pulmonary Tuberculosis II

1.3K
Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
1.3K
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

468
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
468
Pulmonary Tuberculosis V01:28

Pulmonary Tuberculosis V

523
Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
523
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

802
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
802
Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture01:26

Sputum Studies I: Gram Stain, cytology, and Acid-fast smear and culture

536
Sputum studies are a critical part of diagnosing and treating numerous respiratory conditions. These studies involve obtaining sputum samples for analysis to identify pathogenic organisms and assess the presence of abnormal cells indicative of malignant conditions. This lesson will delve into three fundamental sputum studies: Gram Stain, Cytology, and Acid-fast Smear and Culture.
Gram Stain
The Gram Stain is an integral part of sputum studies. It involves the staining of sputum, which permits...
536

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Antimicrobial Resistance in Children With Bloodstream Infections: A Population-Based Study in Stockholm, Sweden.

Acta paediatrica (Oslo, Norway : 1992)·2026
Same author

The complexity of acute mastoiditis in Swedish children.

International journal of pediatric otorhinolaryngology·2025
Same author

Pre-admission virus detection during the COVID-19 pandemic in children with and without symptoms of infection.

Acta paediatrica (Oslo, Norway : 1992)·2024
Same author

The pneumococcal conjugate vaccine had a sustained effect on Swedish children 8 years after its introduction.

Acta paediatrica (Oslo, Norway : 1992)·2024
Same author

Seizures in hospitalised paediatric patients with SARS-CoV-2 and comparison of severity with seizures in hospitalised paediatric patients with other respiratory viruses during the COVID-19 pandemic: a population-based cohort study.

Archives of disease in childhood·2023
Same author

Human bocavirus 1 epidemiology in children in relation to virus load and codetection.

Acta paediatrica (Oslo, Norway : 1992)·2023

Related Experiment Video

Updated: Jan 8, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

19.2K

Tuberculosis and Leprosy in the Past.

Malin Ridell1, Margareta Eriksson2

  • 1Department of Microbiology and Immunology, Institute of Biomedicine, The University, Gothenburg, Sweden.

International Journal of Mycobacteriology
|December 18, 2025
PubMed
Summary

Ancient DNA and lipid analyses reveal tuberculosis (TB) and leprosy were widespread diseases in past populations. Evidence shows TB existed 17,000 years ago, while leprosy dates back over 4000 years.

Keywords:
Leprosypasttuberculosis

More Related Videos

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice
10:32

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice

Published on: March 23, 2014

15.5K
DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat VNTR - Fragment Length Analysis FLA
09:39

DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat VNTR - Fragment Length Analysis FLA

Published on: July 15, 2011

27.7K

Related Experiment Videos

Last Updated: Jan 8, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates
10:04

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

19.2K
Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice
10:32

Optimized Protocols for Mycobacterium leprae Strain Management: Frozen Stock Preservation and Maintenance in Athymic Nude Mice

Published on: March 23, 2014

15.5K
DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat VNTR - Fragment Length Analysis FLA
09:39

DNA Fingerprinting of Mycobacterium leprae Strains Using Variable Number Tandem Repeat VNTR - Fragment Length Analysis FLA

Published on: July 15, 2011

27.7K

Area of Science:

  • Paleopathology
  • Molecular Archaeology
  • Bioarchaeology

Background:

  • New analytical methods have significantly advanced our understanding of ancient diseases.
  • Tuberculosis (TB) and leprosy are key examples of historical diseases studied using these techniques.

Purpose of the Study:

  • To investigate the prevalence and timeline of tuberculosis and leprosy in ancient populations.
  • To explore the origins of TB and the historical distribution of leprosy.

Main Methods:

  • Analysis of ancient DNA extracted from skeletal remains.
  • Lipid analysis of cell wall components from ancient bone samples.
  • Osteological examination of ancient human and animal skeletons.

Main Results:

  • Tuberculosis evidence found in a 17,000-year-old bison and ancient human remains globally, indicating widespread presence.
  • Leprosy identified in Europe from the Middle Ages and in India over 4000 years ago.
  • Co-infections of TB and leprosy detected in historical samples, including a Viking grave.

Conclusions:

  • Tuberculosis was a globally distributed ancient disease, likely originating from environmental nonpathogenic mycobacteria.
  • Leprosy has a long history, with evidence suggesting its presence in India predates its appearance in medieval Europe.
  • Ancient pathogen detection methods provide crucial insights into the evolution and epidemiology of infectious diseases.