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Early Hemodynamic Support in Resource-Limited Settings: Rethinking Vasoactive Delivery in Pediatric Sepsis

Ilana Harwayne-Gidansky1,2

  • 1Division of Critical Care Medicine, Department of Pediatrics, Bernard and Millie Duker Children's Hospital, Albany, NY.

Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
|December 18, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
critical careimplementation sciencelow- and middle-income countriespediatric sepsisseptic shockvasoactive agents

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In pediatric medicine, understanding the renal function and drug elimination nuances is crucial for administering safe and effective treatments. Newborns, in particular, display markedly slower renal functions than adults, profoundly affecting how drugs are cleared from their bodies. This slower drug clearance requires clinicians to extend the dosing intervals for many medications to prevent drug accumulation and toxicity while ensuring therapeutic efficacy.One key area where these adjustments...
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