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Centralized Telemetry Enables Continuous Monitoring to Predict Clinical Deterioration in Infants Hospitalized with

Felipe González Martínez, Cristina Núñez Carretero, Laura García Fernández

    American Journal of Perinatology
    |December 18, 2025
    PubMed

    Insights

    Continuous heart rate (HR) monitoring in infants hospitalized with bronchiolitis can help predict the need for high-flow nasal cannula (HFNC) therapy or pediatric intensive care unit (PICU) admission, aiding early clinical deterioration detection.

    Area of Science:

    • Pediatrics
    • Medical Technology
    • Critical Care Medicine

    Background:

    • Bronchiolitis is a leading cause of infant hospitalization.
    • Early detection of clinical deterioration in infants with bronchiolitis is challenging.
    • Continuous telemetry data offers potential for improved monitoring.

    Purpose of the Study:

    • To analyze continuous longitudinal telemetry data (heart rate and oxygen saturation) in infants hospitalized with bronchiolitis.
    • To evaluate if this monitoring can predict the need for high-flow nasal cannula (HFNC) therapy or pediatric intensive care unit (PICU) admission.

    Main Methods:

    • Retrospective, observational study of infants hospitalized with bronchiolitis.
    • Collected minute-by-minute heart rate (HR) and oxygen saturation (SpO2) data during the first 24 hours.
    • Utilized a mixed-effects model (REML) to analyze longitudinal HR and SpO2 data.

    Main Results:

    • Included 79 infants with 113,760 data points; 16.5% required HFNC, 9% admitted to PICU.
    • Higher HR in the initial hours was observed in patients who required PICU and HFNC (p < 0.01).
    • Mixed model analysis revealed significant differences in HR between groups and over time (p < 0.01).

    Conclusions:

    • Continuous HR monitoring in pediatric wards may help anticipate clinical deterioration in infants with bronchiolitis.
    • Longitudinal telemetry monitoring shows promise for early prediction of critical care needs.
    • Centralized telemetry monitoring could be beneficial in general pediatric wards.
    Abstract

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