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Updated: Jan 8, 2026

Identification of Key Factors Regulating Self-renewal and Differentiation in EML Hematopoietic Precursor Cells by RNA-sequencing Analysis
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Single cell RNAseq signatures refined with combiroc enhance identification of NK cells in blood and solid tissues

Ivan Ferrari1, Saveria Mazzara2,3, Andrea Gobbini1

  • 1Istituto Nazionale Genetica Molecolare "Romeo ed Enrica Invernizzi", Milan, Italy.

Scientific Reports
|December 18, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
BiomarkersCombinatoricsGene signaturesPhenotype overlapR packagescRNA-seq

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RNA-seq03:21

RNA-seq

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RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
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Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
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