Related Experiment Video
Updated: Jan 8, 2026
Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation
Published on: July 5, 2024
Inverse association of alcohol consumption patterns with constipation and diarrhea: a population-based
Haoyan Zhuang1,2, Zhao Guo3, Shiguo Li1,2
1Anorectal Department, Weifang Hospital Of Traditional Chinese Medicine, Weifang, China.
Background:
Constipation and diarrhea are prevalent gastrointestinal health issues that significantly impact productivity and daily life, often leading to psychological problems and exacerbating public health burdens. Alcohol is a commonly consumed beverage worldwide, and previous studies suggest that it may exert certain effects on the gastrointestinal tract. Investigating the relationship between patterns of alcohol consumption and the presence of gastrointestinal symptoms such as constipation or diarrhea can aid in the formulation of public health strategies and improve management plans for alcohol use and gastrointestinal health.
Objective:
To explore the relationship between patterns of alcohol consumption (average daily alcohol consumption and drinking levels) and the presence of gastrointestinal symptoms such as constipation or diarrhea.
Methods:
The study utilized data from the National Health and Nutrition Examination Survey (NHANES) database from 2005 to 2010, enrolling a total of 12,959 eligible participants aged 20 years and older. Multivariate logistic regression analysis was employed to investigate the association of drinking patterns with constipation and diarrhea. Restricted cubic spline (RCS) curves were used to confirm the nonlinear relationship between these variables. Finally, subgroup analyses were conducted to identify high-risk groups and populations with specific effects.
Results:
In this study, a negative correlation was observed between the average daily alcohol consumption and constipation (OR: 0.94, 95% CI: 0.91-0.97; P < 0.001). Similarly, a negative correlation was found between drinking levels and constipation (P < 0.001). These results remained stable even after adjusting for all confounding factors. However, the negative correlation between both average daily alcohol consumption and drinking levels with diarrhea was only present in model 1, and the results became unstable after adjusting for all confounding factors.
Conclusion:
Our study reveals a negative correlation between drinking patterns and both constipation and diarrhea. However, this association warrants further biological research for validation.
More Related Videos
05:12Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
Published on: June 23, 2023
03:25Author Spotlight: Exploring Non-Pharmacological Therapies for Chronic Respiratory Diseases — Linking Intestinal Microbiome Insights to COPD Treatment
Published on: December 27, 2024
Related Concept Videos
01:17Drugs for Treatment of Diarrhea-Predominant IBS
Two specific drugs used in the treatment are alosetron (Lotronex) and eluxadoline (Viberzi). Alosetron, a 5-HT3 antagonist, works by slowing the movement of stools in the gut, reducing bowel...
01:20Drugs Affecting GI Tract Motility: Adsorbents as Antidiarrheal Agents
Adsorbents...
01:21Drugs for Treatment of Constipation-Predominant IBS
01:17Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
01:17Chronic Bowel Disorders: Introduction
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
01:30Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...