Related Experiment Video
Updated: Jan 8, 2026
07:24
Repression of Multiple Myeloma Cell Growth In Vivo by Single-wall Carbon Nanotube SWCNT-delivered MALAT1 Antisense Oligos
Published on: December 13, 2018
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NEAT1: a multifaceted long non-coding RNA in multiple myeloma.
Gabriele Benini1, Sara Taranto1, Margherita Sciumè1
1Clinical Trial Center, Translational Research and Phase I Unit ASST Spedali Civili di Brescia, BS.
Haematologica
|December 19, 2025
Summary
Multiple myeloma, a bone marrow cancer, is currently incurable. Research highlights the long non-coding RNA NEAT1 as a potential biomarker and therapeutic target for this hematologic neoplasm.
Area of Science:
- Hematology
- Oncology
- Molecular Biology
Background:
- Multiple myeloma (MM) is a fatal hematologic neoplasm characterized by uncontrolled plasma cell proliferation in the bone marrow.
- Despite advancements, MM remains an incurable malignancy, necessitating novel therapeutic strategies.
- Long non-coding RNAs (lncRNAs) are emerging as critical regulators in cancer, including MM.
Conclusions:
- NEAT1 plays a significant role in the pathogenesis of multiple myeloma.
- Targeting NEAT1 may offer a novel therapeutic approach for MM patients.
- Further research is warranted to fully elucidate NEAT1's clinical applications in MM.
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