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Updated: Jul 31, 2026

Induction of Invasive Transitional Cell Bladder Carcinoma in Immune Intact Human MUC1 Transgenic Mice: A Model for Immunotherapy Development
Published on: October 30, 2013
Urachal adenocarcinoma: a case report and literature review
Konstantina Kostara1, Lane Palmisano2, Pasha Shenasan1
1Department of Surgery, St. Joseph's University Medical Center, 703 Main St., Paterson, NJ 07503, United States.
Abstract:
Urachal carcinoma is a rare malignant epithelial neoplasm with an estimated incidence of one in 5 million people. Due to the rarity of these cases, no universally accepted staging system or standardized surgical and oncological treatment protocols currently exist. En bloc surgical resection of the umbilicus, urachal ligament, and involved portion of the bladder remains the preferred treatment. The addition of adjuvant chemotherapy may be considered in the setting of metastatic disease. Here, we present a case of urachal adenocarcinoma in a 67-year-old male who initially presented with purulent umbilical drainage.
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