Through the Lens of Experience: A Case Series on Pediatric Neuroblastic Tumors

Neuroblastic tumors are common malignancies in the pediatric population and arise from neural crest cells. Its clinical presentation is spread out over a wide range of symptoms and presents a unique challenge owing to its manifestations and outcomes. This case series explores the clinical and pathological spectrum of neuroblastic tumors in five pediatric patients treated at a quaternary care institute. The cases were reviewed, and their clinical details, histopathology reports, and operative notes were analyzed. Two posterior mediastinal and three adrenal neuroblastic tumors with varying pathology and disease process are discussed. MYCN was doubled in one of the cases and amplified in another. This series highlights the spectrum of various presentations, stratifying the risk groups and early tumor detection and workup in a resource-limited setting.