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Updated: Jan 7, 2026

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Mechanical and Controlled PRP Injections in Patients Affected by Androgenetic Alopecia
Published on: January 27, 2018
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Patients treated with thinner artificial hair implants: a case series
Antonio Scarano1, Maria Vadalà2,3, Sergio Alexandre Gehrke3,4
1Department of Innovative Technologies in Medicine & Dentistry, University of Chieti-Pescara, Chieti, Italy.
Frontiers in Medicine
|December 19, 2025
Summary
This study shows Biofibre® 4.0 artificial hair implants are safe and effective for treating hair loss in men and women. Patients reported high satisfaction with improved aesthetic appearance and psychological well-being.
Area of Science:
- Dermatology
- Plastic Surgery
- Biomaterials Science
Background:
- Artificial biocompatible hair implants offer a solution for alopecia.
- Biofibre® 4.0 is a novel material for hair restoration.
- Clinical evaluation is essential for optimizing safety and efficacy.
Purpose of the Study:
- Assess patient satisfaction with Biofibre® 4.0 hair implants.
- Evaluate scalp hair density and aesthetic perception.
- Determine the rate of hair loss after one year.
Main Methods:
- 15 patients (10 male, 5 female) of diverse ethnicities participated.
- Biofibre® 4.0 artificial hair (0.08mm diameter) was implanted.
- Fiber roots were placed at the galea aponeurotica level.
Main Results:
- Excellent biocompatibility with no allergies or significant skin reactions.
- Mean patient satisfaction score of 3.1 on a 4-point scale.
- High satisfaction reported by 12 out of 15 patients.
Conclusions:
- Biofibre® 4.0 implantation is a safe and effective technique for androgenetic alopecia.
- Improved fiber softness and elasticity enhance tolerability.
- This method improves aesthetic appearance and psychological well-being.

