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Published on: August 16, 2024
Gynandroblastoma With a Juvenile Granulosa Cell Tumor Component Presenting as Ovarian Torsion in a 14-Year-Old Female
Lisa Su1, Jasmine N Jefferson1, Leslie Lopez-Calderon1
1Pathology and Laboratory Medicine, The University of Tennessee Health Science Center, Memphis, USA.
Abstract:
We report a rare case of a 14-year-old female who presented with a left adnexal mass suspected to be torsed based on ultrasonographic findings. She underwent a left salpingo-oophorectomy, and histopathologic evaluation revealed a mixed sex cord stromal tumor, specifically a gynandroblastoma composed of a juvenile granulosa cell tumor and a moderately differentiated Sertoli-Leydig cell tumor (SLCT) component. Although extremely uncommon, gynandroblastoma should be considered in the differential diagnosis when encountering diverse tumor morphology in ovarian masses. The histologic grade of the SLCT component may influence prognosis and should be closely evaluated.
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