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The Use of Steroid Injections for Hand and Wrist Pathologies.
Rosemary J Bell1,2, Rebecca Cervenak3, Molly I Flint4
1Medical Education, University of Queensland, Brisbane, AUS.
Cureus
|December 19, 2025
Summary
Corticosteroid injections are common for hand and wrist pain but lack clear guidelines. While generally safe, rare serious complications exist, necessitating further research for optimal use.
Area of Science:
- Orthopedics
- Rheumatology
- Pharmacology
Background:
- Corticosteroid injections are frequently used for hand and wrist pathologies unresponsive to conservative treatment.
- Existing guidelines for corticosteroid use in hand and wrist conditions are limited.
- Evidence regarding efficacy and safety is variable and often extrapolated from larger joints.
Purpose of the Study:
- To review current practices of corticosteroid use in hand and wrist pathologies.
- To examine the available evidence on the efficacy and safety of corticosteroid injections.
- To compare current evidence with existing British and American guidelines.
Main Methods:
- A comprehensive literature review of PubMed and Cochrane databases was conducted.
- Studies involving corticosteroid use for common adult hand conditions were included.
- Data on dosage, timing, side effects, and complications were extracted and analyzed.
Main Results:
- Corticosteroid injections in the hand and wrist are generally considered safe, with severe side effects being uncommon.
- Isolated cases of serious complications like necrotizing fasciitis and flexor tendon rupture have been reported.
- Recommended maximums include four injections annually at three-month intervals, with betamethasone or methylprednisolone suggested but based on weak evidence.
Conclusions:
- Corticosteroid use for hand and wrist pathologies is prevalent but lacks robust, evidence-based guidelines.
- Optimal dosage, timing, efficacy, and safety profiles require further investigation.
- Targeted research is essential to establish clear, evidence-based treatment protocols for these conditions.
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