Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Parathyroid Glands00:59

The Parathyroid Glands

4.2K
The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
4.2K
The Thyroid Gland01:23

The Thyroid Gland

6.5K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
6.5K
Synthesis and Functions of Calcitonin00:51

Synthesis and Functions of Calcitonin

4.0K
Calcitonin, a vital polypeptide hormone, regulates calcium levels within body fluids. It is released by the parafollicular cells, also known as C cells, situated in the follicular epithelium of the thyroid gland. Calcitonin responds to fluctuations in blood calcium levels and the influence of gastrointestinal hormones like gastrin and cholecystokinin.
The exact mechanisms by which calcitonin operates in calcium homeostasis remain elusive, but its significance is evident in several vital...
4.0K
Hormones and Bone Tissue01:17

Hormones and Bone Tissue

3.6K
The endocrine system produces and secretes hormones, which interact with the skeletal system. These hormones control bone growth, maintain bone once it is formed, and remodel it.
Hormones That Influence Osteoblasts and/or Maintain the Matrix
Several hormones are necessary for controlling bone growth and maintaining the bone matrix. The pituitary gland secretes growth hormone (GH), which, as its name implies, controls bone growth. This happens in several ways: first, it triggers chondrocyte...
3.6K
Functions of Thyroid Hormones01:18

Functions of Thyroid Hormones

4.9K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
4.9K
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

7.1K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
7.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Complications and technical aspects of safe tissue dissection in endoscopic hemithyroidectomy].

Khirurgiia·2024
Same author

[Integration of ICG-fluorescence cholangiography into the safety system of laparoscopic cholecystectomy].

Khirurgiia·2023
Same author

[Tracheobronchial stenting in patients with non-resectable tumors complicated by airway stenosis].

Khirurgiia·2022
Same author

[Technical features of esophageal stent deployment].

Khirurgiia·2021
Same author

[Surgical care during the new coronavirus (Covid-19) pandemic].

Khirurgiia·2020

Related Experiment Video

Updated: Jan 8, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
07:01

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

Published on: April 17, 2013

21.6K

[Oncocytic thyroid adenoma imitating functionally active parathyroid adenoma].

M Sh Mamistvalov1,2, I A Kurganov1, V V Chistyakov2

  • 1Russian University of Medicine, Moscow, Russia.

Khirurgiia
|December 19, 2025
PubMed
Summary

This case highlights a rare oncocytic thyroid adenoma mimicking primary hyperparathyroidism due to an associated parathyroid adenoma. Accurate diagnosis requires vigilance for combined thyroid and parathyroid tumors.

Keywords:
adenomaparathyroid glandthyroid gland

More Related Videos

Spontaneous Murine Model of Anaplastic Thyroid Cancer
05:39

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

2.2K
Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

4.6K

Related Experiment Videos

Last Updated: Jan 8, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
07:01

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma

Published on: April 17, 2013

21.6K
Spontaneous Murine Model of Anaplastic Thyroid Cancer
05:39

Spontaneous Murine Model of Anaplastic Thyroid Cancer

Published on: February 3, 2023

2.2K
Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

4.6K

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Pathology

Background:

  • Follicular thyroid tumors and parathyroid adenomas can present diagnostic challenges.
  • Combined endocrine neoplasms require careful differential diagnosis.

Purpose of the Study:

  • To report a unique case of oncocytic thyroid adenoma mimicking primary hyperparathyroidism.
  • To emphasize the importance of considering combined thyroid and parathyroid gland pathologies.

Main Methods:

  • Surgical intervention for a patient with suspected thyroid and parathyroid disease.
  • Post-operative pathological analysis to confirm tumor types.
  • Clinical and laboratory evaluation for hyperparathyroidism.

Main Results:

  • An oncocytic thyroid adenoma was identified, presenting with symptoms of primary hyperparathyroidism.
  • The patient also had a parathyroid gland adenoma.
  • Multinodular goiter and intrathyroidal parathyroid adenoma complicated the initial diagnosis.

Conclusions:

  • Combined thyroid and parathyroid tumors can mimic each other, necessitating high clinical suspicion.
  • Thorough diagnostic workup, including imaging and laboratory tests, is crucial for differentiating these neoplasms.
  • Surgical management requires careful pre-operative assessment to address both pathologies effectively.