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Impacts on Causes of Perinatal Death After Safer Baby Bundle Implementation in Victoria, Australia
Keeth L B Mayakaduwage1,2,3, Tanya Farrell2, Roshan J Selvaratnam1,2,3
1The Ritchie Centre, Hudson Institute of Medical Research, Clayton, Victoria, Australia.
Insights
The Safer Baby Bundle (SBB) reduced unexplained stillbirths and those from specific perinatal conditions. This initiative shows promise for national expansion to further decrease perinatal mortality.
Area of Science:
- Perinatal Health
- Public Health Interventions
- Obstetrics and Gynecology
Background:
- The Safer Baby Bundle (SBB) was implemented in June 2019.
- SBB is associated with reduced perinatal mortality.
- Early impact assessment on specific causes of death is crucial for intervention refinement.
Purpose of the Study:
- To evaluate changes in the causes of perinatal death before and after SBB implementation in Victoria, Australia.
- To assess the effectiveness of the SBB in reducing stillbirths and neonatal deaths.
- To identify specific causes of perinatal death impacted by the SBB.
Main Methods:
- Retrospective population-based cohort study of singleton births (≥28 weeks gestation) from 2014 to 2020.
- Exclusion of births with congenital anomalies and terminations.
- Comparison of perinatal death causes in pre-SBB (Jan 2014–Jun 2019) and post-SBB (Jul 2019–Dec 2020) periods using chi-squared tests.
Main Results:
- At SBB sites, stillbirths due to specific perinatal conditions decreased (RR: 0.30) and unexplained antepartum fetal deaths declined (RR: 0.53).
- No significant changes in any cause of neonatal death were observed at SBB sites.
- Non-SBB sites showed increased stillbirths from placental dysfunction and antepartum hemorrhage, but decreased neonatal deaths from hypoxic events and neurological conditions.
Conclusions:
- SBB implementation significantly reduced unexplained stillbirths and those from specific perinatal conditions.
- No increase in any cause of neonatal death was observed, supporting SBB's safety.
- Findings support national expansion of SBB, with continued focus on remaining stillbirth causes.
Background:
The Safer Baby Bundle (SBB) was introduced in June 2019 and has been associated with a reduction in perinatal mortality. Assessing its early impact on specific causes of perinatal death can inform future interventions.
Aims:
This study assessed changes in the causes of perinatal death before and after SBB implementation in Victoria, Australia.
Materials And Methods:
A retrospective population-based cohort study included singleton births ≥ 28 weeks' gestation (excluding congenital anomalies and terminations) from 2014 to 2020. Births were categorised into pre-SBB (January 2014-June 2019) and post-SBB (July 2019-December 2020) periods. Chi-squared tests compared changes in perinatal death causes at SBB and non-SBB sites.
Results:
At SBB sites, stillbirths due to specific perinatal conditions decreased from 0.26 to 0.08/1000 (RR: 0.30, 95% CI: 0.11-0.84, p = 0.015), and unexplained antepartum fetal deaths decreased from 0.86 to 0.45/1000 (RR: 0.53, 95% CI: 0.34-0.82, p = 0.003). No significant changes in any cause of neonatal death were observed. In contrast, non-SBB sites saw increases in stillbirths due to placental dysfunction (0.22 to 0.40/1000, RR: 1.80, 95% CI: 1.09-2.95, p = 0.019) and antepartum haemorrhage (0.15 to 0.31/1000, RR: 2.11, 95% CI: 1.18-3.76, p = 0.010). However, neonatal deaths due to hypoxic peripartum events (0.14 to 0.02/1000, RR: 0.12, 95% CI: 0.02-0.89, p = 0.013) and neurological conditions (0.27 to 0.10/1000, RR: 0.38, 95% CI: 0.16-0.88, p = 0.019) declined.
Conclusions:
SBB implementation was associated with a significant reduction in unexplained stillbirths and those due to specific perinatal conditions, without an increase in any cause of neonatal death. These findings support the program's national expansion, with targeted efforts needed to address the remaining causes of stillbirth.
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