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Updated: Jan 8, 2026

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OPN Promotes Hepatocellular Carcinoma Progression Through the p65/c-Myc/CD155 Axis by Suppressing CD8+ T Cell

Jincun Fang1, Liwei Liu1, Zhiying He1

  • 1Department of Tumor Hematology, Affiliated Hospital Group of Guangdong Medical University Panyu He Xian Memorial Hospital/Panyu Women and Children's Medical Center, Guangdong Medical University (Guangzhou Panyu District Maternal and Child Health Hospital), Guangzhou, China.

Immunological Investigations
|December 19, 2025
PubMed
Abstract

Keywords:
CD8+ T cellsNF-κB (p65)/c-Myc/CD155 axishepatocellular carcinoma (HCC)osteopontin (OPN)tumor immune microenvironmenttumor immunotherapy

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