[Pharmacological adherence and cardiometabolic goals in successfully reperfused acute myocardial infarction]

Adherence to treatment in the secondary prevention of ST-elevation myocardial infarction (STEMI) improves survival and quality of life.

To measure treatment adherence and its association with the frequency of achievement of cardiometabolic targets in patients with STEMI.

A total of 157 adults with STEMI < 12 hours, with successful reperfusion, and in phase 3 of cardiac rehabilitation were included. Demographic variables were collected, and adherence as well as achievement of cardiometabolic targets were measured. Univariate, bivariate (chi-square, Student's t test, or Mann-Whitney U test, depending on distribution), and multivariate logistic regression analyses were performed (p < 0.05).

Adherence was 75%, with a higher percentage of patients meeting LDL cholesterol (54% vs. 21%, p < 0.001), triglyceride (79% vs. 46%, p < 0.001), and glycated hemoglobin (63% vs. 23%, p < 0.001) targets compared to the non-adherent group. Adherence was an independent factor for achieving cardiometabolic targets, with an odds ratio (OR) of 9.8 (95% confidence interval [95% CI]: 3.6-16.3; p < 0.001).

Treatment adherence was associated with a higher frequency of achievement of cardiometabolic targets.