Successful resolution of recurrent peritoneal dialysis-related peritonitis by listeria monocytogenes: a case...

Area of Science:

• Nephrology
• Infectious Diseases
• Microbiology

Background:

• Peritoneal dialysis-associated peritonitis (PDAP) is a significant complication.
• Listeria monocytogenes (LM) is an uncommon cause of PDAP, often linked to dietary sources.
• LM peritonitis may present with non-specific symptoms, complicating diagnosis.

Purpose of the Study:

• To report a rare case of recurrent Listeria monocytogenes peritonitis in a peritoneal dialysis patient.
• To discuss the diagnostic challenges and treatment strategies for LM peritonitis.
• To emphasize the importance of considering dietary sources in PDAP etiology.

Main Methods:

• Case presentation of an elderly male peritoneal dialysis patient with recurrent peritonitis.
• Review of clinical manifestations, including abdominal pain, diarrhea, cloudy dialysate, chills, and fever.
• Analysis of treatment outcomes with different antibiotic regimens.

Main Results:

• The patient experienced recurrent peritonitis attributed to Listeria monocytogenes, likely from contaminated food intake.
• Initial treatment with Cefazolin sodium and Ceftazidime was ineffective.
• Successful resolution was achieved using a combination of Vancomycin, Amikacin, and Piperacillin Tazobactam.

Conclusions:

• Recurrent LM peritonitis is a rare but serious complication in peritoneal dialysis.
• Prompt and appropriate antibiotic therapy is crucial for successful management.
• Combination therapy including Vancomycin, Amikacin, and Piperacillin Tazobactam proved effective in this challenging case.