Employment status in people with multiple sclerosis: Profile, dynamic changes and determinants over time
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View abstract on PubMed
Summary
This summary is machine-generated.Many individuals with multiple sclerosis (MS) experience changes in employment status. Factors like age, sex, and disease progression increase the risk of job loss or early retirement.
Area Of Science
- Neurology
- Occupational Health
- Epidemiology
Background
- Employment is a key aspect of quality of life for individuals with multiple sclerosis (MS).
- Understanding factors influencing work status transitions is crucial for providing timely support.
Purpose Of The Study
- To examine work status changes in a large UK multiple sclerosis (MS) cohort.
- To identify demographic, clinical, and other factors associated with employment transitions.
Main Methods
- Utilized data from the Trajectories of Outcome in Neurological Conditions-MS study.
- Employed regression and Classification and Regression Tree (CART) analysis to identify predictive factors for work disability, discontinuity, and drift.
Main Results
- Observed annual increases in work disability (4.0%), discontinuity (3.1%), and drift (1.8%) among 1035 working individuals with MS.
- Identified increased risk of work disability associated with age, work instability, part-time work, and female sex.
- Found that discontinuity was influenced by MS subtype, cognitive impairment, comorbidities, and reduced by disease-modifying therapies.
Conclusions
- Screening for individuals with MS at higher risk of employment loss is feasible in clinical practice.
- Facilitates multidisciplinary team discussions and appropriate referrals to support services.
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