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Synthesis of Bispecific Conjugates by ADP-Ribosyl Cyclases

Sunny H Kim1, Arshad J Ansari1, Lei Zhang1

  • 1Department of Pharmacology and Pharmaceutical Sciences, Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA, USA.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
|December 21, 2025
PubMed
Summary

Scientists developed a novel bispecific agent using CD38 to target cancer cells. This approach enables potent T-cell-mediated anti-cancer immunity by linking T-cell activation with tumor targeting.

Keywords:
Bispecific conjugateCD38immunotherapyprostate cancer

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