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Isolation and characterization of Aureobasidium pullulans from rose rhizosphere: A novel source for skin benefits
Delphine Guillon1, Laurie Verzeaux2, Gayané Azadiguian3
1L'Oréal R&I, Advanced Research, Aulnay-sous-Bois, France.
Objective:
Rhizospheric microorganisms play a crucial role in plant vitality by contributing to nutrient supply and overall plant health. This research focused on a specific yeast isolated from the rhizosphere of Rosa hybrid delflobla and aimed to investigate if a resulting natural active ingredient can have cosmetic benefits, particularly concerning NAD+, a cofactor known to play a vital role in skin longevity.
Methods:
The yeast Aureobasidium pullulans, sampled in the rhizosphere of Rosa hybrid delflobla, was processed to generate a natural active ingredient (INCI: Aureobasidium pullulans ferment). The efficacy of this active ingredient was investigated on NAD+ (nicotinamide adenine dinucleotide) synthesis, a crucial molecule playing a fundamental role in energy metabolism and a multitude of key cellular processes, as well as on cutaneous barrier function and related skin benefits.
Results:
The results of this study demonstrate that the Aureobasidium pullulans ferment increases the NAD+/NADH ratio. Moreover, the expression and synthesis of epidermal differentiation and cohesion markers are stimulated with this natural active ingredient, resulting in an improved barrier function. Clinical results demonstrate that the Aureobasidium pullulans ferment smooths skin microrelief and enhances complexion radiance.
Conclusion:
Altogether, these results reveal that the active ingredient obtained from the Rosa hybrid delflobla rhizosphere (INCI: Aureobasidium pullulans ferment) has highly interesting potential to improve skin resilience and longevity.
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