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Vascular Involvement in Endometriosis and Adenomyosis (Reply to Letter-to-the-Editor)

Linda C Giudice1, Binya Liu1, Juan C Irwin1

  • 1Department of Obstetrics, Gynecology and Reproductive Sciences, University of California San Francisco, San Francisco, CA, U.S.A. 94143.

American Journal of Obstetrics and Gynecology
|December 21, 2025
PubMed
Abstract

No abstract available in PubMed .

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The uterine wall consists of three histological layers: the perimetrium, myometrium, and endometrium. The outermost perimetrium is a thin, serous membrane connected with the broad ligament on the sides, which helps anchor the uterus in the pelvic cavity. The thickest layer, myometrium, is mainly made up of smooth muscle tissue bundles. Its contractions are vital in facilitating the expulsion of the uterine lining, fetus, and placenta during menstruation and childbirth.
The endometrium is the...
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