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Artificial Intelligence in Surgical Research: Transformative Impacts and Evolving Ethical Challenges
Miranda X Morris1, Faris Rustom2, Benjamin Chun3
1Division of Plastic and Reconstructive Surgery, Lahey Hospital & Medical Center, Burlington, MA, USA.
The American Surgeon
|December 22, 2025
Summary
Artificial intelligence (AI) is revolutionizing surgical research with new tools for planning and real-time support. Responsible implementation requires addressing ethical concerns like bias and privacy for trustworthy advancements.
Area of Science:
- Surgical Research
- Artificial Intelligence
- Medical Informatics
Background:
- Artificial intelligence (AI) is increasingly integrated into surgical research, enhancing areas like preoperative planning and intraoperative guidance.
- Advances in computing power and data analytics enable AI applications beyond retrospective analysis to real-time clinical decision support.
- Large language models (LLMs) are also being utilized for literature synthesis, data analysis, and manuscript preparation in surgical research.
Purpose of the Study:
- To review recent advancements in AI applications within surgical research.
- To examine the critical ethical challenges posed by the rapid integration of AI in surgery.
- To propose frameworks for the responsible implementation of AI in surgical research.
Main Methods:
- Literature review of recent technological advancements in AI for surgical research.
- Analysis of current AI use cases, including 3D planning, scheduling, and ambient scribes.
- Examination of ethical concerns such as algorithmic bias, data privacy, and accountability.
Main Results:
- AI is driving innovation in surgical planning, intraoperative guidance, workflow optimization, and academic productivity.
- Current applications include AI-assisted 3D planning, automated scheduling, and ambient scribe technology.
- LLMs are increasingly applied to literature synthesis, data analysis, and manuscript development.
Conclusions:
- The rapid integration of AI in surgical research presents significant ethical challenges, including bias, privacy, opacity, and accountability.
- Structured frameworks emphasizing transparency, equity, and patient safety are crucial for responsible AI implementation.
- Ensuring ethical considerations are addressed will facilitate trustworthy AI-driven improvements in surgical care.
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