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  11. Evaluation Of Critical Parameters For Optimizing The Therapeutic Approach In Pediatric Patients With Compartment Syndrome During The 2023 Türkiye Earthquake Disaster.
  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Paediatrics
  9. Infant And Child Health
  11. Evaluation Of Critical Parameters For Optimizing The Therapeutic Approach In Pediatric Patients With Compartment Syndrome During The 2023 Türkiye Earthquake Disaster.

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Evaluation of critical parameters for optimizing the therapeutic approach in pediatric patients with compartment syndrome during the 2023 Türkiye earthquake disaster.

Elif Emel Erten1, Can İhsan Öztorun2, Ahmet Ertürk2

  • 1Department of Pediatric Surgery, University of Health Sciences, Ankara Bilkent City Hospital, Ankara-Türkiye.

Ulusal Travma Ve Acil Cerrahi Dergisi = Turkish Journal of Trauma & Emergency Surgery : TJTES
|December 22, 2025

View abstract on PubMed

Summary
This summary is machine-generated.

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Prolonged entrapment and high creatine kinase (CK) and myoglobin levels predict severe outcomes in pediatric earthquake victims with compartment syndrome. Early intervention and wound care improve limb salvage rates.

Area of Science:

  • Disaster Medicine
  • Pediatric Traumatology
  • Musculoskeletal Injuries

Background:

  • The 2023 Türkiye earthquake caused numerous pediatric musculoskeletal trauma cases.
  • Compartment syndrome (CS) and crush injuries were common complications in child victims.
  • Identifying predictors of severity, renal failure, and limb loss is crucial.

Purpose of the Study:

  • To identify clinical and biochemical parameters predicting disease severity, renal failure, and limb loss in pediatric earthquake victims.
  • To evaluate the effectiveness of therapeutic interventions in managing CS and crush-related complications.

Main Methods:

  • Retrospective analysis of 103 pediatric patients (0-18 years) admitted post-earthquake.
  • Evaluation of demographic data, entrapment duration, and laboratory values (CK, myoglobin, AST, ALT, urea, potassium).
  • Analysis of interventions including fasciotomy, negative-pressure wound therapy (NPWT), hyperbaric oxygen therapy (HBOT), hemodialysis, and amputation, using ROC analyses for outcome prediction.

    • Main Results:

    • 45.6% of patients developed CS, with 12.6% requiring amputation and 18.4% needing hemodialysis for acute kidney injury.
    • Entrapment >8 hours, CK >10,000 U/L, and myoglobin >4,000 ng/mL predicted renal failure, fasciotomy, and amputation.
    • NPWT and HBOT in necrotic limbs contributed to an 82% limb salvage rate; no amputations occurred in non-necrotic limbs.

    Conclusions:

    • Prolonged entrapment and elevated CK/myoglobin levels are reliable indicators of adverse outcomes in pediatric CS patients post-earthquake.
    • Timely decompression and structured wound management (NPWT, HBOT) are vital for limb salvage when early surgery is not feasible.
    • Early recognition and intervention are key to improving survival and limb salvage in mass casualty events.