Related Experiment Video
Updated: Jan 8, 2026
Complete Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma Type IIIb
Published on: January 17, 2025
Neoadjuvant Chemotherapy in Resectable Biliary Tract Cancer: A Systematic Review and Metanalysis
Rafael Alvim Pereira1, Gabriel Barcellos2, Gabriel Lenz3
1Department of Internal Medicine, Hospital Santa Casa, São José dos Campos, SP, Brazil.
Background And Objectives:
The benefit of neoadjuvant chemotherapy in resectable biliary tract cancer remains unclear.
Methods:
A systematic review and meta-analysis of 23 studies (n = 11,344) compared neoadjuvant chemotherapy with upfront surgery.
Results:
Neoadjuvant therapy improved overall survival (HR = 0.69) and R0 resection rates (OR = 1.30) without increasing postoperative morbidity or mortality.
Conclusions:
Neoadjuvant chemotherapy may improve survival and surgical outcomes in resectable biliary tract cancer.
More Related Videos
07:36Laparoscopic Common Bile Duct Exploration in Patients with a Previous History of Biliary Tract Surgery
Published on: February 10, 2023
07:44Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022