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Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue
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The PI3K/AKT/mTOR pathway in scar remodeling and keloid formation: mechanisms and therapeutic perspectives

Jing Liu1, Junfei Yan1, Shengbin Qi1

  • 1Plastic Surgery Center, Shijiazhuang People's Hospital, Shijiazhuang, China.

Frontiers in Pharmacology
|December 22, 2025
PubMed

Keywords:
PI3K/Akt/mTOR pathwaydrug delivery platformsextracellular matrixfibroblast proliferationhypertrophic scarkeloidnon-coding RNAstargeted therapy

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