Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Overview of Microscopy Techniques

Overview of Microscopy Techniques

The early pioneers of microscopy opened a window into the invisible world of microorganisms. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes that leveraged nonvisible light, such as fluorescence microscopy that uses an ultraviolet light source and electron microscopy that uses short-wavelength electron beams. These advances significantly improved magnification, image resolution, and contrast. By comparison, the...

Super-resolution Fluorescence Microscopy

Super-resolution Fluorescence Microscopy

Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Surgical strategies for spontaneous intracerebral hemorrhage: a Bayesian network meta-analysis of randomized controlled trials.

Frontiers in neurology·2026

Same author

Artificial intelligence for detecting fetal orofacial clefts and advancing medical education.

Nature communications·2026

Same author

Screening for atrial fibrillation using an ECG monitoring patch among the elderly population in rural China: a single-arm study.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2026

Same author

Associations between estimated glucose disposal rate and peripheral artery disease: evidence from the UK Biobank and NHANES.

Nutrition & metabolism·2026

Same author

Establishment and characterization of a novel human ampullary carcinoma cell line derived from a Chinese patient.

BMC cancer·2026

Same author

Research Advances in Acupuncture Treatment for Chronic Pain.

Pain management nursing : official journal of the American Society of Pain Management Nurses·2026

Same journal

Recent Progress in on-Demand Transfer-Enabled Integration of Wavelength-Scale Light Sources.

Nanophotonics (Berlin, Germany)·2026

Same journal

Tunable skyrmion bag textures in surface phonon polariton lattices.

Nanophotonics (Berlin, Germany)·2026

Same journal

All-Optical Diffractive Operators for Rapid, Computer-Free Morphological Transformations.

Nanophotonics (Berlin, Germany)·2026

Same journal

Tunable Skyrmion, Meron, and Skyrmion Bag Textures in Surface Phonon Polariton Lattices.

Nanophotonics (Berlin, Germany)·2026

Same journal

Deep-Subwavelength Slot-Enhanced Broadband Dynamic Camouflage Metasurface Across the S, C, X, and Ku Bands.

Nanophotonics (Berlin, Germany)·2026

Same journal

Machine Learning-Driven Cooling Window Design Beyond Hyperbolic Metamaterials.

Nanophotonics (Berlin, Germany)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jan 8, 2026

High-speed Particle Image Velocimetry Near Surfaces

High-speed Particle Image Velocimetry Near Surfaces

Published on: June 24, 2013

Metasurface-based Fourier ptychographic microscopy.

Cheng Hung Chu^1,2, Hao-Pin Chiu¹, Cheng Yu³

¹Institute of Medical Device and Imaging, National Taiwan University, Taipei 10051, Taiwan.

Nanophotonics (Berlin, Germany)

|December 22, 2025

Summary

This summary is machine-generated.

We developed a compact meta-optics microscope using meta-Fourier ptychography (FP) and AI to achieve high-resolution imaging. This portable system overcomes limitations of traditional FP, enabling faster and more accurate quantitative phase imaging.

Keywords:

Fourier ptychographic microscopy metalens quantitative phase imaging residual convolutional neural network

More Related Videos

A Multimodal Wide-Field Fourier-Transform Raman Microscope

A Multimodal Wide-Field Fourier-Transform Raman Microscope

Published on: December 30, 2025

Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution

Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution

Published on: August 16, 2012

Related Experiment Videos

Last Updated: Jan 8, 2026

High-speed Particle Image Velocimetry Near Surfaces

High-speed Particle Image Velocimetry Near Surfaces

Published on: June 24, 2013

A Multimodal Wide-Field Fourier-Transform Raman Microscope

A Multimodal Wide-Field Fourier-Transform Raman Microscope

Published on: December 30, 2025

Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution

Lensfree On-chip Tomographic Microscopy Employing Multi-angle Illumination and Pixel Super-resolution

Published on: August 16, 2012

Area of Science:

Optics and Photonics
Computational Imaging
Biomedical Engineering

Background:

Meta-optics enable miniaturized, high-performance imaging systems.
Fourier ptychography (FP) offers high-resolution quantitative phase imaging but traditionally requires bulky optics and mechanical scanning.
Existing FP methods face challenges in portability and speed.

Purpose of the Study:

To develop a compact and fast Fourier ptychography (FP) microscopy platform.
To overcome the limitations of traditional FP systems using meta-optics and artificial intelligence.
To demonstrate high-resolution quantitative phase imaging with improved portability and speed.

Main Methods:

Integration of a 4-f metalens system for miniaturization.
Utilized a programmable thin-film transistor (TFT) panel for angle-diverse illumination without mechanical movement.
Employed a residual convolutional neural network (RCNN) for single-shot, high-resolution phase reconstruction from low-resolution inputs.

Main Results:

Achieved nearly twofold resolution improvement (7.81 µm to 3.91 µm).
Demonstrated accurate quantitative phase recovery with <10% error on phase standards.
Showcased reliable dry-mass estimation of H1975 cells with <12% average deviation.

Conclusions:

The meta-FP platform offers a fast, compact, and high-performance solution for quantitative phase imaging.
Integration of metasurface optics and AI accelerates imaging and enhances resolution.
Potential applications include live-cell imaging, microfluidic monitoring, and point-of-care diagnostics.