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Updated: Jan 8, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Conceptualizing clinical expertise in evidence-based practice: a narrative literature review with implications for
Deborah Kopansky-Giles1,2, Jonathan Murray3, Jessica M Parish4
1Canadian Memorial Chiropractic College, Department of Research and Innovation, Toronto, ON.
Objective:
This review aimed to explore clinical expertise within evidence-based practice (EBP) by examining contemporary definitions of clinical expertise, how it can be acquired and developed over time, and its role within EBP.
Methods:
PubMed, Web of Science, and Scopus databases were searched for literature on clinical expertise published between January 2016 and August 2024. Titles and abstracts were screened for relevance. Full-text review was conducted for papers deemed potentially relevant.
Results:
23 articles were included in this review. Clinical expertise receives different treatments across literature. However, a commonality is that clinical expertise requires proficiency, skill, and clinical judgement that can be acquired only through clinical experience, collaboration, and hands-on clinical practice. Operating within Haynes' model of EBP, clinical expertise is central to integrating patient preferences and bridging the gap between standardized objective evidence and personalized care.
Conclusions:
Clinical expertise represents the core of integrating EBP to inform clinical decision-making and is developed through experience and keeping current with research.
Author’S Note:
This paper is one of seven in a series exploring contemporary perspectives on the application of the evidence-based framework in chiropractic care. The Evidence Based Chiropractic Care (EBCC) initiative aims to support chiropractors in their delivery of optimal patient-centred care. We encourage readers to review all papers in the series.
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