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Updated: Jan 8, 2026

Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Enhancing evidence-based chiropractic practice: bridging the knowledge-to-action gap for the needs of community-based
Caroline Brereton1, Peter C Emary2, Carol Cancelliere3
1Ontario Chiropractic Association, Toronto, ON.
Objective:
To summarize key factors of knowledge translation (KT) and offer actionable recommendations to improve uptake and application of evidence-based practice (EBP) in chiropractic care.
Methods:
We conducted a narrative review searching for KT literature in PubMed, Web of Science, and Scopus from January 2016 to August 2024. Titles and abstracts were screened for eligibility and relevant articles underwent full-text review. We used an expert consensus approach to form our recommendations.
Results:
We identified KT barriers and facilitators at individual, collegial, and organizational levels. Recommendations include advocating for individual clinicians to pursue continuous education and mentorship, and for professional organizations to support KT funding and foster supportive and collaborative environments for individual clinicians to engage in KT.
Conclusions:
To bridge the knowledge-to-action (KTA) gap in the chiropractic profession, chiropractors should engage in learning environments to develop necessary EBP skills, while associations should focus on supporting and incentivizing chiropractors to enhance their KT abilities.
Author’S Note:
This paper is one of seven in a series exploring contemporary perspectives on the application of the evidence-based framework in chiropractic care. The Evidence Based Chiropractic Care (EBCC) initiative aims to support chiropractors in their delivery of optimal patient-centred care. We encourage readers to review all papers in the series.
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