Related Experiment Video
Updated: Jan 8, 2026
In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Synchronous angiomyolipoma with epithelial cysts and clear cell renal cell carcinoma: a case report
Jian Wang1, Chengde Ren2, Ziyang Qiang2
1Department of Clinical Medicine, Qinghai University, Xining, Qinghai, China.
Background:
Angiomyolipoma with Epithelial Cysts (AMLEC) is a rare renal tumor that has been established as a separate pathological entity in recent years. Existing literature has focused on its histological origin, molecular features, and imaging characteristics. To our knowledge, this is the first reported case of AMLEC coexisting with clear cell renal cell carcinoma (ccRCC).
Case Presentation:
A 37-year-old male presented with lumbar pain and persistent gross hematuria. Imaging revealed tumor rupture with hemorrhage, initially suggestive of cystic renal cell carcinoma. However, postoperative pathology and immunohistochemistry confirmed a diagnosis of AMLEC combined with ccRCC.
Conclusion:
AMLEC is a rare subtype of angiomyolipoma (AML) that typically lacks adipose tissue, with an epithelial component likely derived from dilated renal tubules. Its unique histological features and immunohistochemical staining are key to pathological diagnosis. This report also reviews prior cases of AMLEC and synchronous renal tumors, offering a valuable reference for clinical diagnosis and management.
More Related Videos
05:36Comparing Metastatic Clear Cell Renal Cell Carcinoma Model Established in Mouse Kidney and on Chicken Chorioallantoic Membrane
Published on: February 8, 2020
06:29Microfluidic Co-culture of Renal Healthy and Tumor Epithelium to Model Kidney Cancer Progression
Published on: January 31, 2025
Related Concept Videos
01:20Renal Corpuscle
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
01:24Renal Tubule and Collecting Duct
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...