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Innovations in mandibular advancement splint therapy for obstructive sleep apnoea.
Anna Mohammadieh1,2, Benjamin Tong1,2, Philip De Chazal2
1Department of Respiratory and Sleep Medicine, Royal North Shore Hospital, Sydney, NSW, Australia.
Frontiers in Sleep
|December 22, 2025
Summary
Mandibular advancement splint (MAS) therapy is a leading treatment for obstructive sleep apnoea (OSA). This review covers innovations in MAS design, fabrication, and data collection for improved sleep apnoea management.
Area of Science:
- Dental Sleep Medicine
- Respiratory Medicine
- Biomedical Engineering
Background:
- Obstructive sleep apnoea (OSA) is a prevalent sleep disorder.
- Mandibular advancement splint (MAS) therapy has become a primary non-surgical treatment for OSA since the 1990s.
Purpose of the Study:
- To review current and emerging innovations in Mandibular Advancement Splint (MAS) therapy.
- To assess the impact of these innovations on obstructive sleep apnoea (OSA) management.
Main Methods:
- Literature review of advancements in MAS therapy.
- Analysis of innovations in design, customization, fabrication, titration, and data collection.
Main Results:
- Significant revisions and advances have occurred in MAS therapy since its inception.
- Innovations span customisation, fabrication techniques, titration protocols, and predictive response models.
- Integration of data collection technology is a key emerging trend.
Conclusions:
- MAS therapy continues to evolve with technological and design innovations.
- These advancements offer potential for more personalized and effective obstructive sleep apnoea management.
- Further research into emerging innovations will refine MAS therapy's role in OSA treatment.
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