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Updated: Jan 7, 2026

Modeling Brain Metastases Through Intracranial Injection and Magnetic Resonance Imaging
Published on: June 7, 2020
Bone Metastases of Breast Cancer in the Skull Base: An Unusual Metastatic Spread
Mariana S Beja1, Joana Marques2, Vasco S Cardoso3
1Obstetrics and Gynecology, Unidade Local de Saúde (ULS) - Lisboa Ocidental, Lisbon, PRT.
Abstract:
Breast cancer is a prevalent malignancy and a leading cause of cancer-related mortality among women. A subset of women present with primary disseminated disease, with bone being a frequent site of metastatic involvement. However, metastatic spread to the base of the skull is rare, asymptomatic, and often difficult to diagnose. The authors present a case of an elderly female patient in her early 80s with advanced breast cancer who had bone metastases limited to the base of the skull at the time of diagnosis.

