Related Experiment Video
Updated: Jan 8, 2026

07:27
Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
25.1K
Acute Asymptomatic Pericarditis Following Olanzapine Overdose
Mohsin Raza1, David Ballack2, Jasleen Kaur3
1Department of Psychiatry, Dover Behavioral Health System, Dover, USA.
Cureus
|December 22, 2025
Summary
Olanzapine overdose can cause acute pericarditis, a rare but serious heart inflammation. Early ECG changes may be the only sign, even without chest pain, highlighting the need for cardiac monitoring in overdose cases.
Area of Science:
- Cardiology
- Psychiatry
- Pharmacology
Background:
- Olanzapine is an atypical antipsychotic effective for schizophrenia and bipolar disorder.
- Olanzapine use is linked to metabolic side effects and cardiovascular disease.
- Acute pericarditis is a rare adverse reaction to olanzapine overdose.
Related Concept Videos
Pericarditis II: Clinical Features and Diagnostic Tests
258
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
258
Pericarditis IV: Nursing Management
293
Pericarditis, an inflammation of the pericardium, necessitates diligent nursing management to ensure effective patient care and recovery. The initial step in managing pericarditis is a comprehensive patient medical assessment.The patient reports chest pain aggravated by breathing, coughing, and swallowing, which worsens when lying supine. The pain often improves when sitting up and leaning forward. Additional symptoms may include fever, malaise, and, in severe cases, signs of heart failure.
293
Pericarditis I: Introduction
292
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
292
Psychosis: Goals of Pharmacotherapy
436
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
436
Myocarditis III: Medical Management
155
Myocarditis: Comprehensive Medical ManagementMyocarditis, the heart muscle inflammation, requires a comprehensive medical management strategy that addresses the underlying cause, provides supportive care, manages symptoms, and reduces cardiac workload.Infections and Autoimmune CausesAdminister appropriate antimicrobial therapy when an infectious agent causes myocarditis. For instance, penicillin treats infections caused by Group A Streptococcus. In cases where autoimmune processes are...
155
Pericarditis III: Medical Management
276
The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...
276

