Stroke caused by cerebral amyloid angiopathy: a case of difficult diagnosis

Rocío Campos Gamarra1, Carla Villanueva Colina1, Jimmy Palacios-García1,2

  • 1Universidad Peruana Cayetano Heredia, Lima, Peru.

Dementia & Neuropsychologia
|December 22, 2025
PubMed

Cerebral amyloid angiopathy is a common cause of intracerebral hemorrhage, most often occurring in older adults and in patients with dementia. One of its main differential diagnoses is hypertensive intracerebral hemorrhage. This is a case report of a hypertensive male patient who presented to the emergency department with short-term amnesia and Broca's aphasia. The initial diagnosis was hemorrhagic stroke of hypertensive etiology. However, subsequent diagnostic tests revealed that the bleeding was due to amyloid angiopathy. This case highlights the similarities and differences in the diagnosis and management of both etiologies, emphasizing the importance of establishing an accurate and timely differential diagnosis.

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