Neonatal diet and growth outcomes in hospitalised very preterm infants: an observational study in middle income countries in Africa, Asia, and Latin America
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
View abstract on PubMed
Summary
This summary is machine-generated.In middle-income countries, infants born very preterm or with very low birth weight (VLBW) fed a mixed diet showed slower weight gain than those fed only formula. Further research is needed for optimal feeding strategies.
Area Of Science
- Neonatalogy
- Pediatric Nutrition
- Global Health
Background
- Data on feeding practices for vulnerable newborns in middle-income countries are scarce.
- Small, vulnerable newborns require specific nutritional support during hospitalization.
Purpose Of The Study
- To analyze growth indicators in very preterm or very low birth weight (VLBW) infants.
- To assess the association between in-hospital diet and growth in these infants across 12 middle-income countries.
Main Methods
- An observational cohort study included 35,843 infants born at 22-29 weeks' gestation or VLBW.
- Linear regression analyzed changes in weight and head circumference z-scores based on diet at discharge (human milk only, mixed, formula only).
- Adjustments were made for confounders, with stratification by birth weight and fetal growth status.
Main Results
- Eighty-four percent of infants received some human milk at discharge.
- Weight z-scores declined in all groups, with the slowest decline in the formula-only group (1.17) compared to mixed (1.32) and human milk-only (1.40) groups.
- Mixed diet feeding was associated with slower weight gain compared to formula-only feeding.
Conclusions
- Human milk consumption is prevalent at discharge for VLBW infants in middle-income settings.
- Infants on a mixed diet experienced slower weight gain than those on formula alone.
- Intervention studies are crucial to optimize nutrient delivery for infants receiving human milk.
These videos have been matched automatically. Contact us if they are not relevant.
These videos have been matched automatically. Contact us if they are not relevant.
Related Concept Videos
Microorganisms exhibit diverse oxygen requirements and growth patterns driven by their metabolic strategies and environmental adaptations. Oxygen, while essential for many organisms, can also be toxic under certain conditions, shaping how microorganisms grow and survive.Oxygen Requirements of MicroorganismsMicroorganisms are classified based on their ability to use or tolerate oxygen:● Obligate aerobes like Mycobacterium tuberculosis need oxygen for energy production, as it serves as the...
Understanding the physiological differences in the pediatric population is crucial for effective pharmacotherapy. Neonates, infants, and children exhibit significant variations in gastric pH, gastric emptying time, intestinal transit time, and biliary function. These variations profoundly affect oral drug absorption, necessitating a nuanced approach to pediatric dosing.Neonates present with a unique physiological profile, having a gastric pH greater than 4 and faster and more irregular gastric...
Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Drug distribution in the pediatric population exhibits unique challenges and considerations due to the physiological differences between children, particularly neonates and infants, and adults. A crucial aspect of pediatric pharmacology is understanding how these differences impact the pharmacokinetics of various drugs, necessitating age-specific dosing strategies to ensure efficacy and safety.Neonates and infants have a higher total body water content, ~75%–90% of their body weight,...
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...