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Related Experiment Video

Updated: Jan 8, 2026

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Author Spotlight: Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration

Published on: May 26, 2023

MULTIMODAL IMAGING OF VITELLIFORM LESION IN MACULAR TELANGIECTASIA TYPE 2.

Amrita Pradhan¹, Mukesh Jain², Ankeeta Baliarsingh¹

¹Department of VitreoRetina, Aditya Birla Sankara Nethralaya, Kolkata, West Bengal, India.

Retinal Cases & Brief Reports

|December 22, 2025

Summary

Multimodal imaging revealed vitelliform lesions in macular telangiectasia type 2. Fundus autofluorescence is highly sensitive for detecting these deposits in this condition.

Keywords:

fundus auto fluorescence macular telangiectasia (Mac tel) type 2 optical coherence tomography angiography vitelliform lesions

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Last Updated: Jan 8, 2026

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Published on: January 21, 2018

Area of Science:

Ophthalmology
Medical Imaging

Background:

Macular telangiectasia type 2 (MacTel 2) is a retinal vascular disorder.
Vitelliform lesions are typically associated with other macular diseases.

Purpose of the Study:

To evaluate the utility of multimodal imaging in identifying vitelliform lesions in MacTel 2.
To assess the sensitivity of different imaging techniques for these lesions.

Main Methods:

The study utilized color fundus photography, optical coherence tomography angiography (OCTA), fundus autofluorescence (FAF), and fundus fluorescein angiography (FFA).
These imaging modalities were employed to examine eyes diagnosed with MacTel 2.

Main Results:

Vitelliform lesions were identified in two cases of MacTel 2.
The presence of these lesions was confirmed through multimodal imaging analysis.

Conclusions:

Vitelliform deposits can occur in eyes affected by MacTel 2.
Fundus autofluorescence (FAF) demonstrated high sensitivity in detecting vitelliform lesions within the context of MacTel 2.