Precision and efficacy in congenital cataract surgery: a retrospective study of the 27-gauge vitrectomy system

Maura Mancini1, Alessandro Meduri2, Claudio Brancato3

  • 1Department of Biomedical Sciences, Ophthalmology Clinic, University of Messina, Via 27 Luglio 65, Messina, Italy. maura.mancini94@gmail.com.

International Ophthalmology
|December 22, 2025
PubMed

Insights

The 27-gauge vitrectomy system offers precise and safe congenital cataract surgery in infants, demonstrating effective outcomes and minimal complications. This minimally invasive approach shows promise for pediatric eye care.

Area of Science:

  • Ophthalmology
  • Pediatric Surgery
  • Microsurgery

Background:

  • Congenital cataracts are a leading cause of treatable blindness in infants.
  • Early surgical intervention is crucial for visual development.
  • Minimally invasive techniques are sought to improve safety and outcomes in pediatric cataract surgery.

Purpose of the Study:

  • To evaluate the precision, safety, and efficacy of congenital cataract surgery using the 27-gauge vitrectomy system in infants.
  • To assess the impact of this technique on intraocular pressure and visual function.
  • To document intraoperative and postoperative complications associated with the 27-gauge system.

Main Methods:

  • Retrospective analysis of 44 eyes from 22 infants (3-5 months old) with bilateral congenital cataracts.
  • Assessment of intraocular pressure, corneal diameters, axial length, and complications.
  • Evaluation of visual function through behavioral responses; minimum 6-month follow-up.

Main Results:

  • Significant reduction in intraocular pressure (15.8 to 12.2 mmHg, p<0.001).
  • Average surgical duration of 30 minutes.
  • Minimal, transient complications: conjunctival hyperemia (30%), anterior chamber reaction (12%); no major complications like retinal detachment or glaucoma.

Conclusions:

  • The 27-gauge vitrectomy system enables precise congenital cataract surgery in infants.
  • This technique is associated with low complication rates and effective postoperative results.
  • Further prospective studies are recommended to confirm long-term safety and efficacy.
Abstract