Related Experiment Video
Updated: Jan 8, 2026

A Mouse Model of Ankle-Subtalar Complex Joint Instability
Published on: October 28, 2022
The Prevalence of Subtalar Arthritis Following Pilon Fractures
Raveena Joshi1, Surbhi Srinivas1, Colin O'Neill1
1Foot & Ankle Research and Innovation Lab (FARIL), Department of Orthopaedic Surgery, Massachusetts General Brigham, Harvard Medical School, Boston, Massachusetts.
Background:
Pilon fractures result in substantial morbidity and are associated with a high rate of ankle arthritis. However, literature is scarce regarding the prevalence of posttraumatic subtalar arthritis. Tibiotalocalcaneal (TTC) arthrodesis, or hindfoot nailing, is increasingly used for comminuted pilon fractures, which often involve the subtalar joint. This study aimed to determine the prevalence and severity of posttraumatic subtalar arthritis, to better understand the implications of this surgical technique in these cases.
Methods:
Patients who sustained a pilon fracture and underwent open reduction and internal fixation were retrospectively identified. The patients were categorized into 4 groups on the basis of the time interval between the date of injury and the latest available radiographs: <12, 12 to 24, 25 to 48, and >forty-eight months. The Kellgren-Lawrence (K-L) and NSS (None, Some, Severe) grading systems were used to evaluate the radiographs. Postoperative computed tomography (CT) scans, when available, were similarly graded using the CT Ankle Osteoarthritis (CTAO) system. Pearson correlation, chi-square, Mann-Whitney U, and Welch t tests were used. P < 0.05 was considered significant.
Results:
The study included 473 patients (mean age, 46.15 ± 7.50 years, 293 male and 180 female). The cohort was composed of 80.3% White and 15.8% non-White, with 3.9% missing data.(Patient age at the time of injury (p < 0.001) and at the time of imaging (p < 0.001), smoking status (p = 0.01), steroid use (p = 0.04), Charlson Comorbidity Index (CCI) (p = 0.003), AO/OTA classification (p = 0.03), and time from injury to final imaging (p = 0.004) were significantly correlated with the K-L grade. Group 3 was found to have a higher mean K-L grade than Group 1 (by 0.34, 95% confidence interval [CI]: 0.03 to 0.66; p = 0.04) and Group 2 (by 0.39, 95% CI: 0.05 to 0.73; p = 0.02). Group 4 had a higher K-L grade than Group 1 (by 0.37, 95% CI: 0.08 to 0.66; p = 0.01) and Group 2 (by 0.42, 95% CI: 0.11 to 0.73; p = 0.01). The CTAO score demonstrated meaningful correlation between subtalar arthritis and age at both the time of injury (p = 0.004) and the time of final CT (p = 0.01).
Conclusions:
Multiple patient-based factors including age, smoking status, steroid use, CCI, AO/OTA classification, and the time interval since injury were significantly associated with the development of subtalar arthritis, as assessed using the K-L grade, after pilon fracture. This suggests that acute hindfoot nailing as an index treatment option for pilon fractures may have fewer clinical ramifications than has been anticipated on the basis of its violation of the subtalar joint.
Level Of Evidence:
Prognostic Level III . See Instructions for Authors for a complete description of levels of evidence.
More Related Videos
09:01Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach
Published on: January 24, 2018
07:24Autologous Microfractured and Purified Adipose Tissue for Arthroscopic Management of Osteochondral Lesions of the Talus
Published on: January 23, 2018
Related Concept Videos
Ankle Joint
Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...