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A Concise Approach to Enantioselective Synthesis of Euolutchuols A, B, and D and Their Structure Assignment

Sravya Surendran1, Chandrendu Krishnalekha Chandran1, Reyno Rathinam Stephen1

  • 1School of Chemistry, Indian Institute of Science Education and Research, Thiruvananthapuram, Kerala 695551, India.

The Journal of Organic Chemistry
|December 22, 2025
PubMed

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Conjugated systems containing an even number of π-electron pairs undergo a conrotatory ring closure. For example, thermal electrocyclization of (2E,4E)-2,4-hexadiene, a conjugated diene containing two π-electron pairs, gives trans-3,4-dimethylcyclobutene.
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